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Stacks / Over 40

The Over-40 Program

The complete "feel like I used to" protocol — rebuild the hormonal and cellular foundation age erodes, add the over-40 specific layer, and finish with the full optimization build.

Three systems decline together after 40 — the growth-hormone pulse (down more than half from your 20s), cellular NAD+ (roughly halved by middle age), and recovery speed. Most men attack one symptom at a time; this program rebuilds the whole floor first, then adds the over-40-specific layer, then the complete optimization build for men who want the entire system running.

The Foundation — everyone starts here

The Over-40 Layer

The Complete Optimal Build

The full program at a glance

Layer Compound How it's run
Foundation CJC-1295/Ipamorelin blend 200 mcg pre-bed
Foundation NAD+ 100 mg daily
Foundation BPC-157/TB-500 blend 500 mcg daily
Over-40 MOTS-c 2.5 mg 3×/week
Over-40 DSIP 200 mcg pre-bed
Over-40 Epithalon 15-day course, 2×/year
Optimal PT-141 1 mg as needed
Optimal Tesamorelin 1.5 mg daily
Optimal Glutathione 400 mg 3×/week
Optimal 5-Amino-1MQ 100 mg daily (caps)

The GH pair works on a months timescale — commit to 12 weeks minimum before judging. The Supply Builder sizes the whole program vial-by-vial for the duration you choose.

For the women reading this

Everything here applies over-40 women identically — the GH pulse, NAD+, and recovery declines are the same biology. Run Standard tier, and swap PT-141 guidance for its women's-approved framing (it's literally a female medication first). The Women's Program reshuffles these same pieces skin-and-energy-first.

Research protocols, not a prescription — talk to a physician before touching anything.

Compounds in this program

Growth Hormone Axis

CJC-1295 (no DAC)

A growth-hormone-releasing-hormone analog that prompts your pituitary to release its own GH in natural pulses — almost always paired with Ipamorelin.

Growth Hormone Axis

Ipamorelin

The cleanest of the GH secretagogues — triggers a growth-hormone pulse without meaningfully raising hunger or cortisol. CJC-1295's standard partner.

Energy & Longevity

NAD+

Not technically a peptide — the cellular energy coenzyme itself, injected to restore levels that fall ~50% between youth and middle age. The longevity-circuit staple.

Recovery & Repair

BPC-157

The most-discussed recovery peptide — studied for tendon, ligament, muscle, and gut repair. The usual first compound for anyone training hard with nagging injuries.

Recovery & Repair

TB-500

BPC-157's usual partner — studied for flexibility, tissue repair, and reducing inflammation across the whole body rather than one site.

Weight & Metabolic

MOTS-c

The "exercise in a vial" research peptide — encoded in mitochondrial DNA, studied for insulin sensitivity, endurance, and metabolic flexibility.

Sleep & Recovery

DSIP

The sleep peptide — studied since the 1970s for deepening slow-wave sleep, which is where every other kind of recovery actually happens.

Energy & Longevity

Epithalon

The telomere peptide — a four-amino-acid compound from Russian longevity research, studied for telomerase activation and sleep-hormone normalization.

Men's Health

PT-141

The libido peptide — works through the nervous system rather than blood flow, which is exactly why it's studied where the little blue pill does nothing.

Growth Hormone Axis

Tesamorelin

The most clinically proven GHRH analog — an FDA-approved drug (for HIV-related belly fat) that research circles study for visceral fat specifically.

Immune & Resilience

Glutathione

The body's own master antioxidant — a tripeptide on every IV-therapy and med-spa menu, studied for detoxification, recovery, and oxidative stress.

Weight & Metabolic

5-Amino-1MQ

The oral metabolism molecule — a small NNMT inhibitor studied for raising cellular NAD+ and re-firing stubborn fat metabolism. Capsules, not needles.