Peptide Library / Growth Hormone Axis
Ipamorelin
Also known as: —
The cleanest of the GH secretagogues — triggers a growth-hormone pulse without meaningfully raising hunger or cortisol. CJC-1295's standard partner.
| Typical research dose | 100–300 mcg |
|---|---|
| Frequency | 1–3× daily (fasted) |
| Route | Subcutaneous injection |
| Cycle length | 8–12 weeks, then break |
Figures reflect protocols commonly reported in the research community — not a prescription or a recommendation.
What it is
Ipamorelin is a five-amino-acid growth-hormone secretagogue: it mimics ghrelin at the pituitary and triggers a clean GH pulse. "Clean" is its whole reputation — older compounds in this class also spiked cortisol (stress hormone) and prolactin; ipamorelin is selective enough that it largely doesn't.
What the research looks at
- GH pulse without side signals — human and animal work shows GH release with minimal cortisol/prolactin movement, which is why it displaced older secretagogues.
- Body composition & recovery — the downstream GH/IGF-1 effects: fat oxidation, lean-mass support, connective-tissue recovery.
- Bone density — animal studies show increased bone mineral density.
- Sleep — reinforcing the natural nighttime GH pulse with pre-bed dosing.
How protocols are commonly structured
Almost always run with CJC-1295 no DAC — the two act on different receptors and the combined pulse is larger than either alone. Typical: 100–200 mcg ipamorelin + 100 mcg CJC, same syringe, fasted, pre-bed as the anchor dose; up to 3× daily in aggressive protocols. 8–12 week runs with breaks.
Reconstitution & storage
Lyophilized powder; bacteriostatic-water reconstitution (calculator), refrigerate after mixing, ~4 weeks.
Research protocols, not a prescription — talk to a physician before touching anything.