Peptide Library / Growth Hormone Axis
CJC-1295 (no DAC)
Also known as: Modified GRF (1-29), Mod GRF
A growth-hormone-releasing-hormone analog that prompts your pituitary to release its own GH in natural pulses — almost always paired with Ipamorelin.
| Typical research dose | 100 mcg |
|---|---|
| Frequency | 1–3× daily (fasted; pre-bed dose is the anchor) |
| Route | Subcutaneous injection |
| Cycle length | 8–12 weeks, then break |
Figures reflect protocols commonly reported in the research community — not a prescription or a recommendation.
What it is
CJC-1295 without DAC (properly called Modified GRF 1-29) is a tweaked version of the first 29 amino acids of your body's own growth-hormone-releasing hormone. The "no DAC" matters: it acts in short pulses that mimic natural GH rhythm, rather than keeping levels elevated around the clock the way the DAC version does.
What the research looks at
- GH and IGF-1 elevation — human studies show meaningful increases in GH pulse amplitude and downstream IGF-1.
- Body composition — the practical interest: research on GH-axis stimulation covers fat loss (especially with fasted dosing), lean-mass retention, and recovery.
- Sleep quality — GH release is tied to deep sleep; pre-bed dosing is studied as reinforcing that natural nighttime pulse.
How protocols are commonly structured
The standard research pairing is 100 mcg CJC-1295 + 100–200 mcg Ipamorelin in the same syringe, fasted, with the pre-bed dose considered the anchor. Once daily (pre-bed) is the baseline protocol; two or three daily doses (morning fasted / post-training / pre-bed) is the aggressive version. Runs of 8–12 weeks with a break are typical. Combined CJC+Ipamorelin blend vials exist for exactly this pairing.
Fasted matters: carbohydrates and fats blunt the GH pulse, so protocols keep food about 2 hours away from a dose where practical.
Reconstitution & storage
Lyophilized powder; bacteriostatic-water reconstitution (calculator), refrigerate after mixing, use within ~4 weeks.
Research protocols, not a prescription — talk to a physician before touching anything.